Abstract 2

The Journal of Orthopedic and Sports Physical Therapy, 4:103-108, 1982.

Introduction of Antiinflammatory Drugs by Iontophoresis Double Blind Study

Lawrence E. Bertolucci, MA, PT, ATC Bertolucci Physical Therapy Rehabilitation Agency, Inc. Citrus Heights, California
A double blind study was performed on 53 patients in introducing antiinflammitory drugs by iontophoresis. The objective was to see if local iontophoreic administration of an antiinfalmmatory drug to patients with tendonitis at the shoulder joint would achieve results similar to those obtained by local injection of the drug. [Four treatments were provided to each patient]. Patients below the age of 45 years with shoulder dysfunction related to primary tendonitis responded to iontophoresis steroid administration. Patients in the age group above 45 years with a primary diagnosis of cervical degenerative change demonstrated less pain relief in shoulder tendonitis whether the steroids were administered by local injection or by iontophoresis.
?It appears that iontophoresis has many advantages overt local injection. These advantages may be classified as follows:

(1) The method permits consistent drug delivery.
(2) A low systemic dose is administered.
(3) The treatment is noninvasive. The sterility barrier of the skin is not compromised which is of particular importance when corticosteriod drugs are used.
(4) The treatment is painless. Pain due to needle insertion and tissue tension caused by subcutaneous injection of a fluid volume is not produced.
(5) The treatment is nontraumatic. Tissue damage due to needle penetration and subcutaneous injection of a bolus fluid is avoided.
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